Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 961
Gene Symbol: CD47
CD47 		0.070 Biomarker disease BEFREE ω3-PUFAs may be an effective therapy for the chemoprevention and treatment of human pancreatic cancer. and IAP. 22213040 2011
Entrez Id: 3375
Gene Symbol: IAPP
IAPP 		0.050 Biomarker disease BEFREE ω3-PUFAs may be an effective therapy for the chemoprevention and treatment of human pancreatic cancer. and IAP. 22213040 2011
Entrez Id: 250
Gene Symbol: ALPP
ALPP 		0.040 Biomarker disease BEFREE ω3-PUFAs may be an effective therapy for the chemoprevention and treatment of human pancreatic cancer. and IAP. 22213040 2011
Entrez Id: 248
Gene Symbol: ALPI
ALPI 		0.040 Biomarker disease BEFREE ω3-PUFAs may be an effective therapy for the chemoprevention and treatment of human pancreatic cancer. and IAP. 22213040 2011
Entrez Id: 84061
Gene Symbol: MAGT1
MAGT1 		0.040 Biomarker disease BEFREE ω3-PUFAs may be an effective therapy for the chemoprevention and treatment of human pancreatic cancer. and IAP. 22213040 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker disease BEFREE γ-T3 inhibited the in vitro proliferation of pancreatic cancer cell lines with variable p53 status and potentiated gemcitabine-induced apoptosis. 20864511 2010
Entrez Id: 2520
Gene Symbol: GAST
GAST 		0.100 Biomarker disease BEFREE αv integrin is a new gastrin target in pancreatic cancer models and contributes to gastrin effects on cell adhesion. 22110279 2011
Entrez Id: 84634
Gene Symbol: KISS1R
KISS1R 		0.020 Biomarker disease BEFREE α-Bisabolol Inhibits Invasiveness and Motility in Pancreatic Cancer Through KISS1R Activation. 26851012 2016
Entrez Id: 56159
Gene Symbol: TEX11
TEX11 		0.100 AlteredExpression disease BEFREE Zn<sup>2+</sup> transporters of the ZIP/SLC39A and ZnT/SLC30A families are dysregulated in all major GI organ cancers, in particular, ZIP4 up-regulation in pancreatic cancer (PC). 31636470 2019
Entrez Id: 55630
Gene Symbol: SLC39A4
SLC39A4 		0.100 AlteredExpression disease BEFREE Zn<sup>2+</sup> transporters of the ZIP/SLC39A and ZnT/SLC30A families are dysregulated in all major GI organ cancers, in particular, ZIP4 up-regulation in pancreatic cancer (PC). 31636470 2019
Entrez Id: 84619
Gene Symbol: ZGPAT
ZGPAT 		0.010 AlteredExpression disease BEFREE Zn<sup>2+</sup> transporters of the ZIP/SLC39A and ZnT/SLC30A families are dysregulated in all major GI organ cancers, in particular, ZIP4 up-regulation in pancreatic cancer (PC). 31636470 2019
Entrez Id: 1613
Gene Symbol: DAPK3
DAPK3 		0.010 AlteredExpression disease BEFREE Zn<sup>2+</sup> transporters of the ZIP/SLC39A and ZnT/SLC30A families are dysregulated in all major GI organ cancers, in particular, ZIP4 up-regulation in pancreatic cancer (PC). 31636470 2019
Entrez Id: 2030
Gene Symbol: SLC29A1
SLC29A1 		0.070 AlteredExpression disease BEFREE ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin α3β1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells. 31711924 2020
Entrez Id: 6935
Gene Symbol: ZEB1
ZEB1 		0.100 AlteredExpression disease BEFREE ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin α3β1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells. 31711924 2020
Entrez Id: 472
Gene Symbol: ATM
ATM 		0.100 Biomarker disease BEFREE Zhang and colleagues demonstrate that inhibiting DNA repair by pharmacologic blockade or siRNA silencing of ataxia telangiectasia mutated (ATM) increases type I IFN release via a cGAS/STING-independent, SRC-dependent mechanism in models of pancreatic cancer. 31371279 2019
Entrez Id: 4152
Gene Symbol: MBD1
MBD1 		0.070 Biomarker disease BEFREE ZEB1 silenced SIRT3 expression <i>via</i> interaction with MBD1 to promote aerobic glycolysis in pancreatic cancer. 30487699 2018
Entrez Id: 23410
Gene Symbol: SIRT3
SIRT3 		0.050 AlteredExpression disease BEFREE ZEB1 silenced SIRT3 expression <i>via</i> interaction with MBD1 to promote aerobic glycolysis in pancreatic cancer. 30487699 2018
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		0.100 Biomarker disease BEFREE YY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways. 31631174 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE YY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways. 31631174 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.100 Biomarker disease BEFREE YY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways. 31631174 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		0.100 Biomarker disease BEFREE YY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways. 31631174 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 Biomarker disease BEFREE YM155 induces EGFR suppression in pancreatic cancer cells. 22723871 2012
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.400 GeneticVariation disease BEFREE Yet, it is not fully elucidated whether the risk for pancreatic cancer attributed to BRCA1 is similar to the high risk conferred by BRCA2. 18439109 2008
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.400 GeneticVariation disease BEFREE Yet, it is not fully elucidated whether the risk for pancreatic cancer attributed to BRCA1 is similar to the high risk conferred by BRCA2. 18439109 2008
Entrez Id: 406998
Gene Symbol: MIR216A
MIR216A 		0.040 AlteredExpression disease BEFREE YB-1 expression promotes pancreatic cancer metastasis that is inhibited by microRNA-216a. 28782557 2017